Cargando…

PD-L1 monoclonal antibody-conjugated nanoparticles enhance drug delivery level and chemotherapy efficacy in gastric cancer cells

BACKGROUND: Docetaxel (DOC) is widely used as a chemotherapy drug for various tumors, including gastric cancer (GC), but the clinical application of DOC has been limited due to the hydrophobicity of the drug. We aimed to formulate a multifunctional nanoparticle (NP) system to reduce the side effects...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xu, Shijie, Cui, Fangbo, Huang, Dafu, Zhang, Dinghu, Zhu, Anqing, Sun, Xia, Cao, Yiming, Ding, Sheng, Wang, Yao, Gao, Eryun, Zhang, Fenglin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302817/ https://www.ncbi.nlm.nih.gov/pubmed/30587982 http://dx.doi.org/10.2147/IJN.S175340

Ejemplares similares

BRCAA1 monoclonal antibody conjugated fluorescent magnetic nanoparticles for in vivo targeted magnetofluorescent imaging of gastric cancer
por: Wang, Kan, et al.
Publicado: (2011)

Efficacy and Specificity of a Monoclonal Antibody‐Drug Conjugate in Chemotherapy by Intratumoral Injection
por: Kitamura, Kazuya, et al.
Publicado: (1992)

Studies on polyethylene glycol-monoclonal antibody conjugates for fabrication of nanoparticles for biomedical applications
por: Fisusi, Funmilola, et al.
Publicado: (2020)

Antibody-conjugated nanoparticles for target-specific drug delivery of chemotherapeutics
por: Kumari, Mamta, et al.
Publicado: (2023)

Monoclonal Antibodies and Antibody Drug Conjugates in Multiple Myeloma
por: Radocha, Jakub, et al.
Publicado: (2021)

A Polyethylenimine-Containing and Transferrin-Conjugated Lipid Nanoparticle System for Antisense Oligonucleotide Delivery to AML
por: Yuan, Yiming, et al.
Publicado: (2016)

Brain Cancer Chemotherapy through a Delivery System across the Blood-Brain Barrier into the Brain Based on Receptor-Mediated Transcytosis Using Monoclonal Antibody Conjugates
por: Tashima, Toshihiko
Publicado: (2022)

PD-L1 monoclonal antibody-decorated nanoliposomes loaded with Paclitaxel and P-gp transport inhibitor for the synergistic chemotherapy against multidrug resistant gastric cancers
por: Yu, Jinling, et al.
Publicado: (2020)

HAI-178 antibody-conjugated fluorescent magnetic nanoparticles for targeted imaging and simultaneous therapy of gastric cancer
por: Wang, Can, et al.
Publicado: (2014)

Intravenous Delivery of RNA Encoding Anti-PD-1 Human Monoclonal Antibody for Treating Intestinal Cancer
por: Wu, Lipei, et al.
Publicado: (2022)

Amphiphilic irinotecan–melampomagnolide B conjugate nanoparticles for cancer chemotherapy
por: Qu, Wenhao, et al.
Publicado: (2020)

High endothelial venules predict response to PD-1 inhibitors combined with anti-angiogenesis therapy in NSCLC
por: Ye, Dafu, et al.
Publicado: (2023)

BTK inhibitor combined with anti-PD-1 monoclonal antibody for the treatment of CD20-negative primary central nervous system lymphoma: A case report
por: Feng, Lan, et al.
Publicado: (2022)

CD44v6 Monoclonal Antibody-Conjugated Gold Nanostars for Targeted Photoacoustic Imaging and Plasmonic Photothermal Therapy of Gastric Cancer Stem-like Cells
por: Liang, Shujing, et al.
Publicado: (2015)

A Comparison of Murine PD-1 and PD-L1 Monoclonal Antibodies
por: Bu, Melissa T., et al.
Publicado: (2022)

Calcium-mineralized polypeptide nanoparticle for intracellular drug delivery in osteosarcoma chemotherapy
por: Li, Ke, et al.
Publicado: (2020)

Targeted Delivery of 5-fluorouracil with Monoclonal Antibody Modified Bovine Serum Albumin Nanoparticles
por: Fadaeian, Ghazal, et al.
Publicado: (2015)

Monoclonal antibody as a targeting mediator for nanoparticle targeted delivery system for lung cancer
por: Wathoni, Nasrul, et al.
Publicado: (2022)

Quercetin and doxorubicin co-delivery using mesoporous silica nanoparticles enhance the efficacy of gastric carcinoma chemotherapy
por: Fang, Jian, et al.
Publicado: (2018)

The development and characterisation of porphyrin isothiocyanate–monoclonal antibody conjugates for photoimmunotherapy
por: Hudson, R, et al.
Publicado: (2005)

Lipid-Drug Conjugates and Nanoparticles for the Cutaneous Delivery of Cannabidiol
por: Zielińska, Aleksandra, et al.
Publicado: (2022)

Folic Acid-Chitosan Conjugated Nanoparticles for Improving Tumor-Targeted Drug Delivery
por: Song, Huijuan, et al.
Publicado: (2013)

Antitumor Activity of Thermosensitive Hydrogels Packaging Gambogic Acid Nanoparticles and Tumor-Penetrating Peptide iRGD Against Gastric Cancer
por: Zhang, Dinghu, et al.
Publicado: (2020)

Granulomatous myositis induced by anti–PD-1 monoclonal antibodies
por: Uchio, Naohiro, et al.
Publicado: (2018)

Identification of a monoclonal antibody that targets PD-1 in a manner requiring PD-1 Asn58 glycosylation
por: Wang, Mingzhu, et al.
Publicado: (2019)

Distinct PD-L1 binding characteristics of therapeutic monoclonal antibody durvalumab
por: Tan, Shuguang, et al.
Publicado: (2017)

Current and emerging monoclonal antibodies, antibody-drug conjugates, and bispecific antibodies in treatment of lymphoma
por: Atallah-Yunes, Suheil Albert, et al.
Publicado: (2022)

Seeing is believing: anti-PD-1/PD-L1 monoclonal antibodies in action for checkpoint blockade tumor immunotherapy
por: Tan, Shuguang, et al.
Publicado: (2016)

Internalisation enhances photo-induced cytotoxicity of monoclonal antibody-phthalocyanine conjugates
por: Carcenac, M, et al.
Publicado: (2001)

Antidermatophytic activity of some newly synthesized arylhydrazonothiazoles conjugated with monoclonal antibody
por: Ouf, Salama A., et al.
Publicado: (2020)

Real‐world clinical outcomes of the combination of anti‐PD‐1 antibody, trastuzumab, and chemotherapy for HER2‐positive gastric/gastroesophageal junction cancer
por: Yang, Ju, et al.
Publicado: (2023)

Gold nanoparticles conjugated with anti-CD133 monoclonal antibody and 5-fluorouracil chemotherapeutic agent as nanocarriers for cancer cell targeting
por: Mohd-Zahid, Manali Haniti, et al.
Publicado: (2021)

Nanoparticles from Gantrez-based conjugates for the oral delivery of camptothecin
por: Huarte, Judit, et al.
Publicado: (2021)

Thiolated Chitosan Conjugated Liposomes for Oral Delivery of Selenium Nanoparticles
por: Selmani, Atiđa, et al.
Publicado: (2022)

Lipid nanoparticle delivery of unmodified mRNAs encoding multiple monoclonal antibodies targeting poxviruses in rabbits
por: Mucker, Eric M., et al.
Publicado: (2022)

PD-1/PD-L1 pathway and angiogenesis dual recognizable nanoparticles for enhancing chemotherapy of malignant cancer
por: Sun, Zhenliang, et al.
Publicado: (2018)

Antibody-Drug Conjugates: The New Frontier of Chemotherapy
por: Ponziani, Sara, et al.
Publicado: (2020)

The combination of anti-KIR monoclonal antibodies with anti-PD-1/PD-L1 monoclonal antibodies could be a critical breakthrough in overcoming tumor immune escape in NSCLC
por: He, Yayi, et al.
Publicado: (2018)

Plant Viral Nanoparticle Conjugated with Anti-PD-1 Peptide for Ovarian Cancer Immunotherapy
por: Gautam, Aayushma, et al.
Publicado: (2021)

Studies on conjugation of Spirogyra using monoclonal culture
por: Ikegaya, Hisato, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_87gvm3djcvs1ihuanogc7d48oe