Protein and Chemical Determinants of BL-1249 Action and Selectivity for K(2P) Channels

[Image: see text] K(2P) potassium channels generate leak currents that stabilize the resting membrane potential of excitable cells. Various K(2P) channels are implicated in pain, ischemia, depression, migraine, and anesthetic responses, making this family an attractive target for small molecule modu...

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Detalles Bibliográficos
Autores principales: Pope, Lianne, Arrigoni, Cristina, Lou, Hubing, Bryant, Clifford, Gallardo-Godoy, Alejandra, Renslo, Adam R., Minor, Daniel L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302903/
https://www.ncbi.nlm.nih.gov/pubmed/30089357
http://dx.doi.org/10.1021/acschemneuro.8b00337

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302903/
https://www.ncbi.nlm.nih.gov/pubmed/30089357
http://dx.doi.org/10.1021/acschemneuro.8b00337

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