Cargando…

Different duration of parathyroid hormone exposure distinctively regulates primary response genes Nurr1 and RANKL in osteoblasts

Parathyroid hormone (PTH) exerts dual effects, anabolic or catabolic, on bone when administrated intermittently or continuously, via mechanisms that remain largely unknown. PTH binding to cells induces PTH-responsive genes including primary response genes (PRGs). PRGs are rapidly induced without the...

Descripción completa

Detalles Bibliográficos
Autores principales: Choi, Hyewon, Magyar, Clara E., Nervina, Jeanne M., Tetradis, Sotirios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6303058/
https://www.ncbi.nlm.nih.gov/pubmed/30576321
http://dx.doi.org/10.1371/journal.pone.0208514