Whole genome variant association across 100 dogs identifies a frame shift mutation in DISHEVELLED 2 which contributes to Robinow-like syndrome in Bulldogs and related screw tail dog breeds

Domestic dog breeds exhibit remarkable morphological variations that result from centuries of artificial selection and breeding. Identifying the genetic changes that contribute to these variations could provide critical insights into the molecular basis of tissue and organismal morphogenesis. Bulldo...

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Detalles Bibliográficos
Autores principales: Mansour, Tamer A., Lucot, Katherine, Konopelski, Sara E., Dickinson, Peter J., Sturges, Beverly K., Vernau, Karen L., Choi, Shannon, Stern, Joshua A., Thomasy, Sara M., Döring, Sophie, Verstraete, Frank J. M., Johnson, Eric G., York, Daniel, Rebhun, Robert B., Ho, Hsin-Yi Henry, Brown, C. Titus, Bannasch, Danika L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6303079/
https://www.ncbi.nlm.nih.gov/pubmed/30521570
http://dx.doi.org/10.1371/journal.pgen.1007850

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6303079/
https://www.ncbi.nlm.nih.gov/pubmed/30521570
http://dx.doi.org/10.1371/journal.pgen.1007850

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