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PremPDI estimates and interprets the effects of missense mutations on protein-DNA interactions
Protein-DNA interactions play important roles in regulations of many vital cellular processes, including transcription, translation, DNA replication and recombination. Sequence variants occurring in these DNA binding proteins that alter protein-DNA interactions may cause significant perturbations or...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6303081/ https://www.ncbi.nlm.nih.gov/pubmed/30533007 http://dx.doi.org/10.1371/journal.pcbi.1006615 |