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PremPDI estimates and interprets the effects of missense mutations on protein-DNA interactions

Protein-DNA interactions play important roles in regulations of many vital cellular processes, including transcription, translation, DNA replication and recombination. Sequence variants occurring in these DNA binding proteins that alter protein-DNA interactions may cause significant perturbations or...

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Detalles Bibliográficos
Autores principales: Zhang, Ning, Chen, Yuting, Zhao, Feiyang, Yang, Qing, Simonetti, Franco L., Li, Minghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6303081/
https://www.ncbi.nlm.nih.gov/pubmed/30533007
http://dx.doi.org/10.1371/journal.pcbi.1006615