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BUB-1 promotes amphitelic chromosome biorientation via multiple activities at the kinetochore

Accurate chromosome segregation relies on bioriented amphitelic attachments of chromosomes to microtubules of the mitotic spindle, in which sister chromatids are connected to opposite spindle poles. BUB-1 is a protein of the Spindle Assembly Checkpoint (SAC) that coordinates chromosome attachment wi...

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Detalles Bibliográficos
Autores principales: Edwards, Frances, Maton, Gilliane, Gareil, Nelly, Canman, Julie C, Dumont, Julien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6303103/
https://www.ncbi.nlm.nih.gov/pubmed/30547880
http://dx.doi.org/10.7554/eLife.40690