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Human-specific ARHGAP11B induces hallmarks of neocortical expansion in developing ferret neocortex

The evolutionary increase in size and complexity of the primate neocortex is thought to underlie the higher cognitive abilities of humans. ARHGAP11B is a human-specific gene that, based on its expression pattern in fetal human neocortex and progenitor effects in embryonic mouse neocortex, has been p...

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Detalles Bibliográficos
Autores principales: Kalebic, Nereo, Gilardi, Carlotta, Albert, Mareike, Namba, Takashi, Long, Katherine R, Kostic, Milos, Langen, Barbara, Huttner, Wieland B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6303107/
https://www.ncbi.nlm.nih.gov/pubmed/30484771
http://dx.doi.org/10.7554/eLife.41241