Genome-wide quantification of the effects of DNA methylation on human gene regulation

Changes in DNA methylation are involved in development, disease, and the response to environmental conditions. However, not all regulatory elements are functionally methylation-dependent (MD). Here, we report a method, mSTARR-seq, that assesses the causal effects of DNA methylation on regulatory act...

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Detalles Bibliográficos
Autores principales: Lea, Amanda J, Vockley, Christopher M, Johnston, Rachel A, Del Carpio, Christina A, Barreiro, Luis B, Reddy, Timothy E, Tung, Jenny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Genetics and Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6303109/
https://www.ncbi.nlm.nih.gov/pubmed/30575519
http://dx.doi.org/10.7554/eLife.37513

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6303109/
https://www.ncbi.nlm.nih.gov/pubmed/30575519
http://dx.doi.org/10.7554/eLife.37513

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