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Genome-wide quantification of the effects of DNA methylation on human gene regulation
Changes in DNA methylation are involved in development, disease, and the response to environmental conditions. However, not all regulatory elements are functionally methylation-dependent (MD). Here, we report a method, mSTARR-seq, that assesses the causal effects of DNA methylation on regulatory act...
Autores principales: | Lea, Amanda J, Vockley, Christopher M, Johnston, Rachel A, Del Carpio, Christina A, Barreiro, Luis B, Reddy, Timothy E, Tung, Jenny |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6303109/ https://www.ncbi.nlm.nih.gov/pubmed/30575519 http://dx.doi.org/10.7554/eLife.37513 |
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