Rigid Basepair Monte Carlo Simulations of One-Start and Two-Start Chromatin Fiber Unfolding by Force

The organization of chromatin in 30 nm fibers remains a topic of debate. Here, we quantify the mechanical properties of the linker DNA and evaluate the impact of these properties on chromatin fiber folding. We extended a rigid basepair DNA model to include (un)wrapping of nucleosomal DNA and (un)sta...

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Detalles Bibliográficos
Autores principales: de Jong, Babette E., Brouwer, Thomas B., Kaczmarczyk, Artur, Visscher, Bert, van Noort, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2018
Materias:
Nucleic Acids and Genome Biophysics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6303278/
https://www.ncbi.nlm.nih.gov/pubmed/30366627
http://dx.doi.org/10.1016/j.bpj.2018.10.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6303278/
https://www.ncbi.nlm.nih.gov/pubmed/30366627
http://dx.doi.org/10.1016/j.bpj.2018.10.007

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