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Genomic analysis identifies frequent deletions of Dystrophin in olfactory neuroblastoma

Olfactory neuroblastoma (ONB) is a rare malignant neoplasm arising in the upper portion of the sinonasal cavity. To better understand the genetic bases for ONB, here we perform whole exome and whole genome sequencing as well as single nucleotide polymorphism array analyses in a series of ONB patient...

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Detalles Bibliográficos
Autores principales: Gallia, Gary L., Zhang, Ming, Ning, Yi, Haffner, Michael C., Batista, Denise, Binder, Zev A., Bishop, Justin A., Hann, Christine L., Hruban, Ralph H., Ishii, Masaru, Klein, Alison P., Reh, Douglas D., Rooper, Lisa M., Salmasi, Vafi, Tamargo, Rafael J., Wang, Qing, Williamson, Tara, Zhao, Tianna, Zou, Ying, Meeker, Alan K., Agrawal, Nishant, Vogelstein, Bert, Kinzler, Kenneth W., Papadopoulos, Nickolas, Bettegowda, Chetan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6303314/
https://www.ncbi.nlm.nih.gov/pubmed/30575736
http://dx.doi.org/10.1038/s41467-018-07578-z