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A structural and dynamic model for the assembly of Replication Protein A on single-stranded DNA

Replication Protein A (RPA), the major eukaryotic single stranded DNA-binding protein, binds to exposed ssDNA to protect it from nucleases, participates in a myriad of nucleic acid transactions and coordinates the recruitment of other important players. RPA is a heterotrimer and coats long stretches...

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Detalles Bibliográficos
Autores principales: Yates, Luke A., Aramayo, Ricardo J., Pokhrel, Nilisha, Caldwell, Colleen C., Kaplan, Joshua A., Perera, Rajika L., Spies, Maria, Antony, Edwin, Zhang, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6303327/
https://www.ncbi.nlm.nih.gov/pubmed/30575763
http://dx.doi.org/10.1038/s41467-018-07883-7