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Prickle1 regulates differentiation of frontal bone osteoblasts

Enlarged fontanelles and smaller frontal bones result in a mechanically compromised skull. Both phenotypes could develop from defective migration and differentiation of osteoblasts in the skull bone primordia. The Wnt/Planar cell polarity (Wnt/PCP) signaling pathway regulates cell migration and move...

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Detalles Bibliográficos
Autores principales: Wan, Yong, Lantz, Brandi, Cusack, Brian J., Szabo-Rogers, Heather L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6303328/
https://www.ncbi.nlm.nih.gov/pubmed/30575813
http://dx.doi.org/10.1038/s41598-018-36742-0