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A virus-encoded type I interferon decoy receptor enables evasion of host immunity through cell-surface binding

Soluble cytokine decoy receptors are potent immune modulatory reagents with therapeutic applications. Some virus-encoded secreted cytokine receptors interact with glycosaminoglycans expressed at the cell surface, but the biological significance of this activity in vivo is poorly understood. Here, we...

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Detalles Bibliográficos
Autores principales: Hernáez, Bruno, Alonso-Lobo, Juan Manuel, Montanuy, Imma, Fischer, Cornelius, Sauer, Sascha, Sigal, Luis, Sevilla, Noemí, Alcamí, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6303335/
https://www.ncbi.nlm.nih.gov/pubmed/30575728
http://dx.doi.org/10.1038/s41467-018-07772-z