Human genome-wide measurement of drug-responsive regulatory activity

Environmental stimuli commonly act via changes in gene regulation. Human-genome-scale assays to measure such responses are indirect or require knowledge of the transcription factors (TFs) involved. Here, we present the use of human genome-wide high-throughput reporter assays to measure environmental...

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Detalles Bibliográficos
Autores principales: Johnson, Graham D., Barrera, Alejandro, McDowell, Ian C., D’Ippolito, Anthony M., Majoros, William H., Vockley, Christopher M., Wang, Xingyan, Allen, Andrew S., Reddy, Timothy E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6303339/
https://www.ncbi.nlm.nih.gov/pubmed/30575722
http://dx.doi.org/10.1038/s41467-018-07607-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6303339/
https://www.ncbi.nlm.nih.gov/pubmed/30575722
http://dx.doi.org/10.1038/s41467-018-07607-x

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