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Osteoblast suppression in multiple myeloma bone disease

Multiple myeloma (MM) is the most frequent cancer to involve the skeleton with patients developing osteolytic bone lesions due to hyperactivation of osteoclasts and suppression of BMSCs differentiation into functional osteoblasts. Although new therapies for MM have greatly improved survival, MM rema...

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Detalles Bibliográficos
Autores principales: Adamik, Juraj, Galson, Deborah L, Roodman, G David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6303385/
https://www.ncbi.nlm.nih.gov/pubmed/30591859
http://dx.doi.org/10.1016/j.jbo.2018.09.001