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Nucleotide-dependent DNA gripping and an end-clamp mechanism regulate the bacteriophage T4 viral packaging motor

ATP-powered viral packaging motors are among the most powerful biomotors known. Motor subunits arranged in a ring repeatedly grip and translocate the DNA to package viral genomes into capsids. Here, we use single DNA manipulation and rapid solution exchange to quantify how nucleotide binding regulat...

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Detalles Bibliográficos
Autores principales: Ordyan, Mariam, Alam, Istiaq, Mahalingam, Marthandan, Rao, Venigalla B., Smith, Douglas E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6303390/
https://www.ncbi.nlm.nih.gov/pubmed/30575768
http://dx.doi.org/10.1038/s41467-018-07834-2