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The microRNA-183/96/182 Cluster is Essential for Stereociliary Bundle Formation and Function of Cochlear Sensory Hair Cells

The microRNA (miR)-183/96/182 cluster plays important roles in the development and functions of sensory organs, including the inner ear. Point-mutations in the seed sequence of miR-96 result in non-syndromic hearing loss in both mice and humans. However, the lack of a functionally null mutant has ha...

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Detalles Bibliográficos
Autores principales: Geng, Ruishuang, Furness, David N, Muraleedharan, Chithra K, Zhang, Jinsheng, Dabdoub, Alain, Lin, Vincent, Xu, Shunbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6303392/
https://www.ncbi.nlm.nih.gov/pubmed/30575790
http://dx.doi.org/10.1038/s41598-018-36894-z