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Synthetic mammalian pattern formation driven by differential diffusivity of Nodal and Lefty

A synthetic mammalian reaction-diffusion pattern has yet to be created, and Nodal-Lefty signaling has been proposed to meet conditions for pattern formation: Nodal is a short-range activator whereas Lefty is a long-range inhibitor. However, this pattern forming possibility has never been directly te...

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Detalles Bibliográficos
Autores principales: Sekine, Ryoji, Shibata, Tatsuo, Ebisuya, Miki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6303393/
https://www.ncbi.nlm.nih.gov/pubmed/30575724
http://dx.doi.org/10.1038/s41467-018-07847-x