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Ethanol represses the expression of methanol-inducible genes via acetyl-CoA synthesis in the yeast Komagataella phaffii

In methylotrophic yeasts, the expression of methanol-inducible genes is repressed by ethanol even in the presence of methanol, a phenomenon called ethanol repression. The mechanism of ethanol repression in Komagataella phaffii (Pichia pastoris) was studied, and acetyl-CoA synthesis from ethanol by s...

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Detalles Bibliográficos
Autores principales: Ohsawa, Shin, Nishida, Susumu, Oku, Masahide, Sakai, Yasuyoshi, Yurimoto, Hiroya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6303403/
https://www.ncbi.nlm.nih.gov/pubmed/30575795
http://dx.doi.org/10.1038/s41598-018-36732-2