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Efficacy of bisphosphonates in specific knee osteoarthritis subpopulations: protocol for an OA Trial Bank systematic review and individual patient data meta-analysis

INTRODUCTION: Randomised clinical trials to date investigating the efficacy of bisphosphonates in knee osteoarthritis (OA) have found divergent results, with a recent meta-analysis finding no superiority of these drugs over placebo. Whether particular patient subgroups are more likely to benefit fro...

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Detalles Bibliográficos
Autores principales: Deveza, Leticia A, Bierma-Zeinstra, Sita M A, van Spil, Willem Evert, Oo, Win Min, Saragiotto, Bruno T, Neogi, Tuhina, van Middelkoop, Marienke, Hunter, David J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6303587/
https://www.ncbi.nlm.nih.gov/pubmed/30573485
http://dx.doi.org/10.1136/bmjopen-2018-023889