Droplet digital PCR for the quantification of Alu methylation status in hematological malignancies

BACKGROUND: Alu repeats, belonging to the Short Interspersed Repetitive Elements (SINEs) class, contain about 25% of CpG sites in the human genome. Alu sequences lie in gene-rich regions, so their methylation is an important transcriptional regulation mechanism. Aberrant Alu methylation has been ass...

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Detalles Bibliográficos
Autores principales: Orsini, Paola, Impera, Luciana, Parciante, Elisa, Cumbo, Cosimo, Minervini, Crescenzio F., Minervini, Angela, Zagaria, Antonella, Anelli, Luisa, Coccaro, Nicoletta, Casieri, Paola, Tota, Giuseppina, Brunetti, Claudia, Ricco, Alessandra, Carluccio, Paola, Specchia, Giorgina, Albano, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6303857/
https://www.ncbi.nlm.nih.gov/pubmed/30579366
http://dx.doi.org/10.1186/s13000-018-0777-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6303857/
https://www.ncbi.nlm.nih.gov/pubmed/30579366
http://dx.doi.org/10.1186/s13000-018-0777-x

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