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The gut microbiota-derived metabolite trimethylamine N-oxide is elevated in Alzheimer’s disease

BACKGROUND: Trimethylamine N-oxide (TMAO), a small molecule produced by the metaorganismal metabolism of dietary choline, has been implicated in human disease pathogenesis, including known risk factors for Alzheimer’s disease (AD), such as metabolic, cardiovascular, and cerebrovascular disease. METH...

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Detalles Bibliográficos
Autores principales: Vogt, Nicholas M., Romano, Kymberleigh A., Darst, Burcu F., Engelman, Corinne D., Johnson, Sterling C., Carlsson, Cynthia M., Asthana, Sanjay, Blennow, Kaj, Zetterberg, Henrik, Bendlin, Barbara B., Rey, Federico E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6303862/
https://www.ncbi.nlm.nih.gov/pubmed/30579367
http://dx.doi.org/10.1186/s13195-018-0451-2