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The gut microbiota-derived metabolite trimethylamine N-oxide is elevated in Alzheimer’s disease
BACKGROUND: Trimethylamine N-oxide (TMAO), a small molecule produced by the metaorganismal metabolism of dietary choline, has been implicated in human disease pathogenesis, including known risk factors for Alzheimer’s disease (AD), such as metabolic, cardiovascular, and cerebrovascular disease. METH...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6303862/ https://www.ncbi.nlm.nih.gov/pubmed/30579367 http://dx.doi.org/10.1186/s13195-018-0451-2 |