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Development and validation of a simplified method to generate human microglia from pluripotent stem cells
BACKGROUND: Microglia, the principle immune cells of the brain, play important roles in neuronal development, homeostatic function and neurodegenerative disease. Recent genetic studies have further highlighted the importance of microglia in neurodegeneration with the identification of disease risk p...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6303871/ https://www.ncbi.nlm.nih.gov/pubmed/30577865 http://dx.doi.org/10.1186/s13024-018-0297-x |