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Development and validation of a simplified method to generate human microglia from pluripotent stem cells

BACKGROUND: Microglia, the principle immune cells of the brain, play important roles in neuronal development, homeostatic function and neurodegenerative disease. Recent genetic studies have further highlighted the importance of microglia in neurodegeneration with the identification of disease risk p...

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Detalles Bibliográficos
Autores principales: McQuade, Amanda, Coburn, Morgan, Tu, Christina H., Hasselmann, Jonathan, Davtyan, Hayk, Blurton-Jones, Mathew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6303871/
https://www.ncbi.nlm.nih.gov/pubmed/30577865
http://dx.doi.org/10.1186/s13024-018-0297-x