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Simvastatin, but not pravastatin, inhibits the proliferation of esophageal adenocarcinoma and squamous cell carcinoma cells: a cell-molecular study

BACKGROUND AND OBJECTIVE: Long-term statin therapy has been shown to protect against several cancers, including esophageal cancer (EC). While the mechanisms underlying this effect are not clear. We investigated the effect of hydrophobic simvastatin and hydrophilic pravastatin on the proliferation of...

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Detalles Bibliográficos
Autores principales: Chen, Yan, Li, Li-Bin, Zhang, Jun, Tang, Du-Peng, Wei, Jing-Jing, Zhuang, Ze-Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6303879/
https://www.ncbi.nlm.nih.gov/pubmed/30579354
http://dx.doi.org/10.1186/s12944-018-0946-7