Cargando…

SIRT6 drives epithelial-to-mesenchymal transition and metastasis in non-small cell lung cancer via snail-dependent transrepression of KLF4

BACKGROUND: Epithelial-to-mesenchymal transition (EMT) contributes to the invasion and metastasis of epithelial tumors. Sirtuin 6 (SIRT6), an NAD-dependent deacetylase, is known to promote metastasis of non-small cell lung cancer (NSCLC). METHODS: In this work, we determined the role of SIRT6 in the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Ziming, Huang, Jia, Shen, Shengping, Ding, Zhenping, Luo, Qingquan, Chen, Zhiwei, Lu, Shun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6303940/ https://www.ncbi.nlm.nih.gov/pubmed/30577808 http://dx.doi.org/10.1186/s13046-018-0984-z

Ejemplares similares

Retraction Note: SIRT6 drives epithelial-to-mesenchymal transition and metastasis in non-small cell lung cancer via snail-dependent transrepression of KLF4
por: Li, Ziming, et al.
Publicado: (2023)

MicroRNA-10b regulates epithelial–mesenchymal transition by modulating KLF4/KLF11/Smads in hepatocellular carcinoma
por: Hujie, Gulibaha, et al.
Publicado: (2018)

Downregulation of CHIP promotes ovarian cancer metastasis by inducing Snail‐mediated epithelial–mesenchymal transition
por: Park, Sun‐Mi, et al.
Publicado: (2019)

Overexpression of SIRT1 promotes metastasis through epithelial-mesenchymal transition in hepatocellular carcinoma
por: Hao, Chong, et al.
Publicado: (2014)

Hypoxia, Snail and incomplete epithelial–mesenchymal transition in breast cancer
por: Lundgren, K, et al.
Publicado: (2009)

The Epithelial-Mesenchymal Transition Factor SNAIL Paradoxically Enhances Reprogramming
por: Unternaehrer, Juli J., et al.
Publicado: (2014)

The structural basis of direct glucocorticoid-mediated transrepression
por: Hudson, William H., et al.
Publicado: (2012)

Gene Transactivation and Transrepression in MYC-Driven Cancers
por: Scafuro, Marika, et al.
Publicado: (2021)

Autophagy regulates hepatocyte identity and epithelial-to-mesenchymal and mesenchymal-to-epithelial transitions promoting Snail degradation
por: Grassi, G, et al.
Publicado: (2015)

AP-2β inhibits hepatocellular carcinoma invasion and metastasis through Slug and Snail to suppress epithelial-mesenchymal transition
por: Yang, Liu, et al.
Publicado: (2018)

Role of SIRT1 in regulation of epithelial-to-mesenchymal transition in oral squamous cell carcinoma metastasis
por: Chen, I-Chieh, et al.
Publicado: (2014)

Effect of KLF17 overexpression on epithelial–mesenchymal transition of gastric cancer cells
por: Li, Shaoyi, et al.
Publicado: (2021)

Restoration of FBP1 suppressed Snail-induced epithelial to mesenchymal transition in hepatocellular carcinoma
por: Liu, Gao-Min, et al.
Publicado: (2018)

Snail1 induces epithelial-to-mesenchymal transition and tumor initiating stem cell characteristics
por: Dang, Hien, et al.
Publicado: (2011)

The SNAIL/miR-128 axis regulated growth, invasion, metastasis, and epithelial-to-mesenchymal transition of gastric cancer
por: Yu, Wei-Wei, et al.
Publicado: (2017)

HECTD1 regulates the expression of SNAIL: Implications for epithelial-mesenchymal transition
por: Wang, Xinggang, et al.
Publicado: (2020)

KLF7 overexpression in human oral squamous cell carcinoma promotes migration and epithelial-mesenchymal transition
por: Ding, Xiaojun, et al.
Publicado: (2017)

SIRT2 inhibits non-small cell lung cancer cell growth through impairing Skp2-mediated p27 degradation
por: Li, Ziming, et al.
Publicado: (2016)

miR-486-5p suppresses prostate cancer metastasis by targeting Snail and regulating epithelial–mesenchymal transition
por: Zhang, Xiaoguang, et al.
Publicado: (2016)

Metastasis‐associated protein 1 promotes epithelial‐mesenchymal transition in idiopathic pulmonary fibrosis by up‐regulating Snail expression
por: Qian, Weibin, et al.
Publicado: (2020)

Huaier polysaccharides suppress triple-negative breast cancer metastasis and epithelial-mesenchymal transition by inducing autophagic degradation of Snail
por: Tian, Yuan, et al.
Publicado: (2021)

The ectopic expression of Snail in MDBK cells does not induce epithelial-mesenchymal transition
por: IZAWA, GENYA, et al.
Publicado: (2015)

Lamp2 inhibits epithelial-mesenchymal transition by suppressing Snail expression in HCC
por: Zheng, Hao, et al.
Publicado: (2018)

Silencing Snail Reverses Epithelial-Mesenchymal Transition and Increases Radiosensitivity in Hypopharyngeal Carcinoma
por: Wang, HaiYan, et al.
Publicado: (2020)

Canonical BMP Signaling Executes Epithelial-Mesenchymal Transition Downstream of SNAIL1
por: Frey, Patrick, et al.
Publicado: (2020)

TPPP3 promote epithelial-mesenchymal transition via Snail1 in glioblastoma
por: Xu, Xu, et al.
Publicado: (2023)

CircSTK3 drives the metastasis of colorectal cancer by regulating epithelial-mesenchymal transition
por: Fan, Boyang, et al.
Publicado: (2023)

Wanted: A New Model for Glucocorticoid Receptor Transactivation and Transrepression
por: Sedwick, Caitlin
Publicado: (2014)

Epithelial–mesenchymal transition in tumor metastasis
por: Yeung, Kay T., et al.
Publicado: (2016)

Lipocalin2 suppresses metastasis of colorectal cancer by attenuating NF-κB-dependent activation of snail and epithelial mesenchymal transition
por: Feng, Meibao, et al.
Publicado: (2016)

Targeting the SPOCK1-snail/slug axis-mediated epithelial-to-mesenchymal transition by apigenin contributes to repression of prostate cancer metastasis
por: Chien, Ming-Hsien, et al.
Publicado: (2019)

KLF4 Plays an Essential Role in Corneal Epithelial Homeostasis by Promoting Epithelial Cell Fate and Suppressing Epithelial–Mesenchymal Transition
por: Tiwari, Anil, et al.
Publicado: (2017)

Epigenomic Reprogramming toward Mesenchymal-Epithelial Transition in Ovarian-Cancer-Associated Mesenchymal Stem Cells Drives Metastasis
por: Fan, Huihui, et al.
Publicado: (2020)

NF-κB–Dependent Snail Expression Promotes Epithelial–Mesenchymal Transition in Mastitis
por: Liu, Haokun, et al.
Publicado: (2021)

SIRT7 suppresses the epithelial-to-mesenchymal transition in oral squamous cell carcinoma metastasis by promoting SMAD4 deacetylation
por: Li, Wenlu, et al.
Publicado: (2018)

Sin3a drives mesenchymal-to-epithelial transition through cooperating with Tet1 in somatic cell reprogramming
por: Feng, Jiabao, et al.
Publicado: (2022)

Elf5 inhibits epithelial mesenchymal transition in mammary gland development and breast cancer metastasis by transcriptionally repressing Snail2/Slug
por: Chakrabarti, Rumela, et al.
Publicado: (2012)

Caveolin-1 enhances brain metastasis of non-small cell lung cancer, potentially in association with the epithelial-mesenchymal transition marker SNAIL
por: Kim, Yeong-Jin, et al.
Publicado: (2019)

Gli1 promotes epithelial–mesenchymal transition and metastasis of non-small cell lung carcinoma by regulating snail transcriptional activity and stability
por: Lei, Xueping, et al.
Publicado: (2022)

KLF4 Induces Mesenchymal–Epithelial Transition (MET) by Suppressing Multiple EMT-Inducing Transcription Factors
por: Subbalakshmi, Ayalur Raghu, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_87oupkfc0l5dto4pej04ubs1k7