MeDEStrand: an improved method to infer genome-wide absolute methylation levels from DNA enrichment data

BACKGROUND: DNA methylation of CpG dinucleotides is an essential epigenetic modification that plays a key role in transcription. Widely used DNA enrichment-based methods offer high coverage for measuring methylated CpG dinucleotides, with the lowest cost per CpG covered genome-wide. However, these m...

Descripción completa

Detalles Bibliográficos
Autores principales: Xu, Jingting, Liu, Shimeng, Yin, Ping, Bulun, Serdar, Dai, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6303941/
https://www.ncbi.nlm.nih.gov/pubmed/30577750
http://dx.doi.org/10.1186/s12859-018-2574-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6303941/
https://www.ncbi.nlm.nih.gov/pubmed/30577750
http://dx.doi.org/10.1186/s12859-018-2574-7

Ejemplares similares