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MeDEStrand: an improved method to infer genome-wide absolute methylation levels from DNA enrichment data
BACKGROUND: DNA methylation of CpG dinucleotides is an essential epigenetic modification that plays a key role in transcription. Widely used DNA enrichment-based methods offer high coverage for measuring methylated CpG dinucleotides, with the lowest cost per CpG covered genome-wide. However, these m...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6303941/ https://www.ncbi.nlm.nih.gov/pubmed/30577750 http://dx.doi.org/10.1186/s12859-018-2574-7 |