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Illuminating the genome-wide activity of genome editors for safe and effective therapeutics
Genome editing holds remarkable promise to transform human medicine as new therapies that can directly address the genetic causes of disease. However, concerns remain about possible undesired biological consequences of genome editors, particularly the introduction of unintended ‘off-target’ mutation...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6303961/ https://www.ncbi.nlm.nih.gov/pubmed/30577870 http://dx.doi.org/10.1186/s13059-018-1610-2 |