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Galactosylated chitosan-functionalized mesoporous silica nanoparticles for efficient colon cancer cell-targeted drug delivery

Targeted drug delivery to colon cancer cells can significantly enhance the therapeutic efficiency. Herein, we developed 5-fluorouracil (5-FU)-loaded amino-functionalized mesoporous silica nanoparticle (MSN-NH(2))-based galactosylated chitosans (GCs), which are galactose receptor-mediated materials f...

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Detalles Bibliográficos
Autores principales: Liu, Wei, Zhu, Yongchao, Wang, Fan, Li, Xue, Liu, Xiaojing, Pang, Jingjing, Pan, Weisan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304116/
https://www.ncbi.nlm.nih.gov/pubmed/30662725
http://dx.doi.org/10.1098/rsos.181027