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Pharmacokinetic interactions and tolerability of berberine chloride with simvastatin and fenofibrate: an open-label, randomized, parallel study in healthy Chinese subjects

PURPOSE: Fenofibrate (Fbt) is a prodrug that has been used to reduce low-density-lipoprotein cholesterol, triglycerides, and increase high-density-lipoprotein cholesterol. Simvastatin (Svt) is a classic lipid-lowering drug that is widely used in the treatment of hypercholesterolemia and hypertriglyc...

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Detalles Bibliográficos
Autores principales: Li, Guofei, Zhao, Mingming, Qiu, Feng, Sun, Yaxin, Zhao, Limei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304249/
https://www.ncbi.nlm.nih.gov/pubmed/30587933
http://dx.doi.org/10.2147/DDDT.S185487