Cytoprotective effects of molsidomine against methotrexate-induced hepatotoxicity: an experimental rat study

INTRODUCTION AND AIM: Methotrexate (Mtx) is an antineoplastic and immunosuppressive drug that may cause hepatotoxicity, whereas molsidomine (Mol) is a vasodilating and antioxidant agent. This study aimed to investigate the potential protective effects of Mol in Mtx-induced liver toxicity in rats. MA...

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Detalles Bibliográficos
Autores principales: Samdanci, Emine Turkmen, Huz, Mustafa, Ozhan, Onural, Tanbek, Kevser, Pamukcu, Esra, Akatli, Ayse Nur, Parlakpinar, Hakan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304250/
https://www.ncbi.nlm.nih.gov/pubmed/30587924
http://dx.doi.org/10.2147/DDDT.S181550

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304250/
https://www.ncbi.nlm.nih.gov/pubmed/30587924
http://dx.doi.org/10.2147/DDDT.S181550

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