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Targeting CDC7 improves sensitivity to chemotherapy of esophageal squamous cell carcinoma

PURPOSE: The cell division cycle 7 (CDC7) is a serine/threonine kinase that is essential for DNA replication in human cells which has been identified to play a critical role in multiple cancer types. However, the expression and clinical significance of CDC7 in ESCC has never been reported. PATIENTS...

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Detalles Bibliográficos
Autores principales: Cao, Ji-Xiang, Lu, Yao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304257/
https://www.ncbi.nlm.nih.gov/pubmed/30588031
http://dx.doi.org/10.2147/OTT.S183629