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The effect of NR4A1 on APP metabolism and tau phosphorylation

Alzheimer's disease (AD) is characterized by senile plaques (SP) composed of β-amyloid protein (Aβ) and neurofibrillary tangles (NFTs) composed of intracellular hyperphosphorylated tau. Recently, nuclear receptor subfamily 4 group A member 1 (NR4A1) was implicated in synaptic plasticity, long-t...

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Detalles Bibliográficos
Autores principales: Zhao, Li-Ge, Tang, Ying, Tan, Jia-Ze, Wang, Jing-Wen, Chen, Guo-Jun, Zhu, Bing-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304284/
https://www.ncbi.nlm.nih.gov/pubmed/30591936
http://dx.doi.org/10.1016/j.gendis.2018.04.008