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The effect of NR4A1 on APP metabolism and tau phosphorylation
Alzheimer's disease (AD) is characterized by senile plaques (SP) composed of β-amyloid protein (Aβ) and neurofibrillary tangles (NFTs) composed of intracellular hyperphosphorylated tau. Recently, nuclear receptor subfamily 4 group A member 1 (NR4A1) was implicated in synaptic plasticity, long-t...
Autores principales: | Zhao, Li-Ge, Tang, Ying, Tan, Jia-Ze, Wang, Jing-Wen, Chen, Guo-Jun, Zhu, Bing-Lin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Chongqing Medical University
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304284/ https://www.ncbi.nlm.nih.gov/pubmed/30591936 http://dx.doi.org/10.1016/j.gendis.2018.04.008 |
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