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Metformin-Induced Mitochondrial Complex I Inhibition: Facts, Uncertainties, and Consequences

Metformin is the most widely prescribed drug to treat patients with type II diabetes, for whom retrospective studies suggest that metformin may have anticancer properties. However, in experiments performed with isolated cells, authors have reported both pro- and anti-apoptotic effects of metformin....

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Detalles Bibliográficos
Autor principal: Fontaine, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304344/
https://www.ncbi.nlm.nih.gov/pubmed/30619086
http://dx.doi.org/10.3389/fendo.2018.00753