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Structural Model of the mIgM B-Cell Receptor Transmembrane Domain From Self-Association Molecular Dynamics Simulations

Antigen binding to B-cell antigen receptors (BCRs) followed by signaling initiates the humoral immune response. The signaling is intimately coupled to nanoclustering of BCRs and their sorting to specific membrane domains, a process that is ruled by interactions between the BCR transmembrane domain a...

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Detalles Bibliográficos
Autores principales: Friess, Mario D., Pluhackova, Kristyna, Böckmann, Rainer A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304377/
https://www.ncbi.nlm.nih.gov/pubmed/30619307
http://dx.doi.org/10.3389/fimmu.2018.02947