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Simultaneous Evaluation of the Influence of Panax ginseng on the Pharmacokinetics of Three Diester Alkaloids after Oral Administration of Aconiti Lateralis Radix in Rats Using UHPLC/QQQ-MS/MS
OBJECTIVES: To investigate whether Panax ginseng (P. ginseng) could affect the metabolism of Diester Alkaloids (DAs) derived from Aconiti Lateralis Radix in vivo. METHODS AND RESULTS: 24 male Sprague-Dawley rats were randomized for 7-day treatment with P. ginseng (low, middle, and high), or vehicle....
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304572/ https://www.ncbi.nlm.nih.gov/pubmed/30622607 http://dx.doi.org/10.1155/2018/6527549 |