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Deleterious alleles in the context of domestication, inbreeding, and selection

Each individual has a certain number of harmful mutations in its genome. These mutations can lower the fitness of the individual carrying them, dependent on their dominance and selection coefficient. Effective population size, selection, and admixture are known to affect the occurrence of such mutat...

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Detalles Bibliográficos
Autores principales: Bosse, Mirte, Megens, Hendrik‐Jan, Derks, Martijn F. L., de Cara, Ángeles M. R., Groenen, Martien A. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304688/
https://www.ncbi.nlm.nih.gov/pubmed/30622631
http://dx.doi.org/10.1111/eva.12691