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Prediction of deleterious mutations in coding regions of mammals with transfer learning

The genomes of mammals contain thousands of deleterious mutations. It is important to be able to recognize them with high precision. In conservation biology, the small size of fragmented populations results in accumulation of damaging variants. Preserving animals with less damaged genomes could opti...

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Detalles Bibliográficos
Autores principales: Plekhanova, Elena, Nuzhdin, Sergey V., Utkin, Lev V., Samsonova, Maria G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304693/
https://www.ncbi.nlm.nih.gov/pubmed/30622632
http://dx.doi.org/10.1111/eva.12607