The Autoantigenic Proinsulin B-Chain Peptide B11-23 Synergises with the 70 kDa Heat Shock Protein DnaK in Macrophage Stimulation

BACKGROUND: Heat shock proteins (Hsp) act as intracellular chaperones and in addition are used as adjuvant in vaccines of peptides complexed with recombinant Hsp. By interacting with autologous peptides, Hsp may promote the induction of autoimmune reactivity. OBJECTIVE: Here, we analysed whether the...

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Detalles Bibliográficos
Autores principales: Blasius, Elias, Gülden, Elke, Kolb, Hubert, Habich, Christiane, Burkart, Volker
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304834/
https://www.ncbi.nlm.nih.gov/pubmed/30622969
http://dx.doi.org/10.1155/2018/4834673

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304834/
https://www.ncbi.nlm.nih.gov/pubmed/30622969
http://dx.doi.org/10.1155/2018/4834673

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