Intrinsic TNFR2 signaling in T regulatory cells provides protection in CNS autoimmunity

TNF is a multifunctional cytokine involved in autoimmune disease pathogenesis that exerts its effects through two distinct TNF receptors, TNFR1 and TNFR2. While TNF- and TNFR1-deficient (but not TNFR2-deficient) mice show very similar phenotypes, the significance of TNFR2 signaling in health and dis...

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Detalles Bibliográficos
Autores principales: Atretkhany, Kamar-Sulu N., Mufazalov, Ilgiz A., Dunst, Josefine, Kuchmiy, Anna, Gogoleva, Violetta S., Andruszewski, David, Drutskaya, Marina S., Faustman, Denise L., Schwabenland, Marius, Prinz, Marco, Kruglov, Andrey A., Waisman, Ari, Nedospasov, Sergei A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304938/
https://www.ncbi.nlm.nih.gov/pubmed/30498033
http://dx.doi.org/10.1073/pnas.1807499115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304938/
https://www.ncbi.nlm.nih.gov/pubmed/30498033
http://dx.doi.org/10.1073/pnas.1807499115

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