Inflammation in the hippocampus affects IGF1 receptor signaling and contributes to neurological sequelae in rheumatoid arthritis

Rheumatoid arthritis (RA) is an inflammatory joint disease with a neurological component including depression, cognitive deficits, and pain, which substantially affect patients’ quality of daily life. Insulin-like growth factor 1 receptor (IGF1R) signaling is one of the factors in RA pathogenesis as...

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Detalles Bibliográficos
Autores principales: Andersson, Karin M. E., Wasén, Caroline, Juzokaite, Lina, Leifsdottir, Lovisa, Erlandsson, Malin C., Silfverswärd, Sofia T., Stokowska, Anna, Pekna, Marcela, Pekny, Milos, Olmarker, Kjell, Heckemann, Rolf A., Kalm, Marie, Bokarewa, Maria I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
PNAS Plus
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305002/
https://www.ncbi.nlm.nih.gov/pubmed/30509997
http://dx.doi.org/10.1073/pnas.1810553115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305002/
https://www.ncbi.nlm.nih.gov/pubmed/30509997
http://dx.doi.org/10.1073/pnas.1810553115

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