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Inflammation in the hippocampus affects IGF1 receptor signaling and contributes to neurological sequelae in rheumatoid arthritis
Rheumatoid arthritis (RA) is an inflammatory joint disease with a neurological component including depression, cognitive deficits, and pain, which substantially affect patients’ quality of daily life. Insulin-like growth factor 1 receptor (IGF1R) signaling is one of the factors in RA pathogenesis as...
Autores principales: | Andersson, Karin M. E., Wasén, Caroline, Juzokaite, Lina, Leifsdottir, Lovisa, Erlandsson, Malin C., Silfverswärd, Sofia T., Stokowska, Anna, Pekna, Marcela, Pekny, Milos, Olmarker, Kjell, Heckemann, Rolf A., Kalm, Marie, Bokarewa, Maria I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305002/ https://www.ncbi.nlm.nih.gov/pubmed/30509997 http://dx.doi.org/10.1073/pnas.1810553115 |
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