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Common ELF1 deletion in prostate cancer bolsters oncogenic ETS function, inhibits senescence and promotes docetaxel resistance

ETS family transcription factors play major roles in prostate tumorigenesis with some acting as oncogenes and others as tumor suppressors. ETS factors can compete for binding at some cis-regulatory sequences, but display specific binding at others. Therefore, changes in expression of ETS family memb...

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Detalles Bibliográficos
Autores principales: Budka, Justin A., Ferris, Mary W., Capone, Matthew J., Hollenhorst, Peter C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305106/
https://www.ncbi.nlm.nih.gov/pubmed/30603056
http://dx.doi.org/10.18632/genesandcancer.182