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Common ELF1 deletion in prostate cancer bolsters oncogenic ETS function, inhibits senescence and promotes docetaxel resistance
ETS family transcription factors play major roles in prostate tumorigenesis with some acting as oncogenes and others as tumor suppressors. ETS factors can compete for binding at some cis-regulatory sequences, but display specific binding at others. Therefore, changes in expression of ETS family memb...
Autores principales: | Budka, Justin A., Ferris, Mary W., Capone, Matthew J., Hollenhorst, Peter C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305106/ https://www.ncbi.nlm.nih.gov/pubmed/30603056 http://dx.doi.org/10.18632/genesandcancer.182 |
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