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Effect of Genotype and Maternal Affective Disorder on Intronic Methylation of FK506 Binding Protein 5 in Cord Blood DNA

A single nucleotide polymorphism (SNP: rs1360780) in FKBP5 (FK506 Binding Protein 5) has been shown to interact with exposure to childhood adversity to promote loss of methylation and increase in gene expression in adults. We asked whether rs1360780 can influence FKBP5 intronic methylation in the co...

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Detalles Bibliográficos
Autores principales: Duis, Jessica, Cox, Olivia H., Ji, Yuelong, Seifuddin, Fayaz, Lee, Richard S., Wang, Xiaobin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305129/
https://www.ncbi.nlm.nih.gov/pubmed/30619472
http://dx.doi.org/10.3389/fgene.2018.00648