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Deguelin induces apoptosis in colorectal cancer cells by activating the p38 MAPK pathway

OBJECTIVES: Deguelin, a rotenoid extracted from Mundulea sericea (Leguminosae), exhibits antitumor effects on several types of human cancers. Due to the limited studies of deguelin on colorectal cancer (CRC), the present study was designed to investigate the antitumor effect of deguelin and to explo...

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Detalles Bibliográficos
Autores principales: Chen, Liubo, Jiang, Kai, Chen, Haiyan, Tang, Yang, Zhou, Xinyi, Tan, Yinuo, Yuan, Ying, Xiao, Qian, Ding, Kefeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305136/
https://www.ncbi.nlm.nih.gov/pubmed/30588113
http://dx.doi.org/10.2147/CMAR.S169476