Novel screen for anti-cancer drugs that elevate chromosome instability (CIN) using human artificial chromosome (HAC)

Human artificial chromosomes (HACs) bearing functional kinetochores have been exploited as promising systems for gene delivery and expression and in studies of different epigenetic modifications on kinetochore structure and function. The HAC-based technology has been also used to develop drug screen...

Descripción completa

Detalles Bibliográficos
Autores principales: Kouprina, Natalay, Pommier, Yves, Larionov, Vladimir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305142/
https://www.ncbi.nlm.nih.gov/pubmed/30627324
http://dx.doi.org/10.18632/oncotarget.26406

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305142/
https://www.ncbi.nlm.nih.gov/pubmed/30627324
http://dx.doi.org/10.18632/oncotarget.26406

Ejemplares similares