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Heparanase inhibitors restrain mesothelioma

Malignant mesothelioma is a highly aggressive form of cancer with poor prognosis due to lack of markers for early diagnosis and resistance to conventional therapies. Heparanase, the sole heparan sulfate (HS) degrading endoglycosidase, regulates multiple biological activities that enhance tumor growt...

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Detalles Bibliográficos
Autores principales: Lapidot, Moshe, Barash, Uri, Vlodavsky, Israel, Pass, Harvey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305150/
https://www.ncbi.nlm.nih.gov/pubmed/30627323
http://dx.doi.org/10.18632/oncotarget.26243